"
PRE 1910
1798 Edward Jenner’s demonstration that inoculation with cowpox could protect against smallpox brought the first hope that the disease could be controlled.
1881 Rubella was accepted as a distinct disease by the International Congress of Medicine.
1885 Dr. Alexander Stewart of Palmerston, Ontario founded a vaccine farm; his cows provided a dependable smallpox vaccine supply for 31 years. In 1916, Connaught Laboratories took over the manufacture of sterile vaccine for uniform, enduring potency.
1888 Tetanus is discovered.
1906 Pertussis bacterium is discovered.
PRE 1910 to 1939
1918 First Canadian pertussis vaccine
1918-1919 “Spanish Flu” influenza pandemic"
https://www.cpha.ca/immunization-timeline
needles first pandemic shortly after, 2+2= 4